In this article, we have examined a Chemical reaction and Radiation Absorption on MHD free convective heat and mass transfer flow of a nanofluid bounded by a semi infinite flat plate with Diffusion thermo(Dufour). The numerical solutions of the boundary layer equations are assumed of oscillatory type. Three types of nano fluids are used namely Ag-water nano fluid, Al₂O₃-water nanofluid, Cu-water and TiO₂ - water nanofluid, with the moving plate with constant velocity U₀. Temperature and concentration are assumed to be fluctuating with time harmonically from a constant mean at the plate surface. We have solved the model equations using two-term perturbation technique. Comprehensive numerical computations are conducted for various values of the parameters describe the flow characteristics and results are illustrated graphically. Skin friction coefficient, wall heat transfer rate and wall mass transfer rate presented in table form.