This investigation deals with an influence of thermal radiation effect on a double-diffusive convection flow of MHD Casson fluid over a stretching vertical surface. The governing partial differential equations are remodeled into ordinary differential equations by using similarity transformation. The ensuing differential equations are resolved numerically by using Runge-Kutta-Fehlberg forth-fifth technique (RKF45 Method). The results of flow and heat analysis on velocity and temperature profiles are given diagrammatically. The numerical values of the local skin friction coefficient, local Nusselt number and local Sherwood number also are shown in a tabular form. Results shows that Casson parameter enhance the velocity and suppress the temperature, concentration fields but opposite effect can be found the presence of Buoyancy force.